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Clinagel – Dosage and Administration
Apply a thin film of Clinagel twice daily to the skin where acne lesions appear. Use enough to cover the entire affected area lightly. Keep container tightly closed.
Clinagel – Contraindications
Clinagel is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
Clinagel – Warnings
Orally and parenterally administered clindamycin has been associated with severe colitis, which may result in patient’s death. Use of the Clinagel results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin. Studies indicate a toxin(s) produced by Clostridia is one primary cause of antibiotic-associated colitis. The colitis is usually characterized by severe persistent diarrhea and severe abdominal cramps and may be associated with the passage of blood and mucus.
Clinagel – Precautions
1. Avoid contact with eyes, nose, mouth, abraded skin or other mucous membranes.
2. Clinagel should be prescribed with caution in atopic individuals. Keep all medicines out of the reach of children.
3. Clinagel has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore, Clinagel should be used with caution in patients receiving such agents.
4. Clinagel should be used during pregnancy only if clearly needed.
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